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Biotech Breakthroughs in Anti-Aging: Decoding the Hallmarks of Aging and the Longevity Code

  • Written by: Telegraph Magazine

Questions like "How to stay young?", "Is NMN really effective?" and "At what age should you start anti-aging care?" have become part of everyday conversation. While many are eager to delay the signs of aging, few truly understand the science behind it.

Dr Fred Zülli (second from right), Founder and Business Development Director of Mibelle Biochemistry, Francis Kwan (second from left), President of HKSCC, Cirrus Chu (first from left), Sales Director of TPMC International Limited and Fanny Cheung (first from right), Director of NF Essential Limited attended the anti-aging seminar.
Dr Fred Zülli (second from right), Founder and Business Development Director of Mibelle Biochemistry, Francis Kwan (second from left), President of HKSCC, Cirrus Chu (first from left), Sales Director of TPMC International Limited and Fanny Cheung (first from right), Director of NF Essential Limited attended the anti-aging seminar.

From Hallmarks of Aging to Scientific Action: Effective Solutions Revealed

To address this knowledge gap, Dr. Fred Zülli, Founder and Business Development Director of Swiss-based biotech company Mibelle Biochemistry, was specially invited to Hong Kong to co-host a seminar with the Hong Kong Society of Cosmetic Chemists. The seminar provided an in-depth look at the latest advancements in Swiss anti-aging research, starting with the 12 "Hallmarks of Aging" theory published in the journal Cell. Dr. Zülli explained how Swiss biotechnology is strategically targeting these biological mechanisms of aging and translating scientific breakthroughs into practical applications in skincare and aesthetic medicine, making age-defying solutions a scientific reality rather than a distant ideal. During the seminar, Dr. Zülli also revealed several truly effective, science-backed methods to combat aging.

Next-Gen Skincare Science: Goji Stem Cell Extract with Dual Action Power for Repair

Exosomes have rapidly emerged as one of the most promising technologies in the skincare industry. According to market data, the global exosome market was valued at over US$140 million in 2023 and is projected to expand at 28% CAGR by 2030. In the U.S., Google searches for "exosomes" surged 17% in one year, evidence of rising consumer interest. Dr. Fred Zülli explains that exosomes are tiny vesicles that are released by cells into the extracellular space, rich in proteins, lipids, and nucleic acids. They can be derived from human, animals or plants cells, including plant stem cells, and reconstructed using liposome technology. These "cellular messengers" play key roles in intercellular communication, immune modulation, and drug delivery. When used in skincare or microneedling treatments, they accelerate wound healing, enhance skin regeneration, and deliver deeper, faster, and safer results. Exosomes offer dual benefits: they strengthen the skin barrier while activating deeper cellular repair, improving overall skin quality, reducing fine lines, and restoring firmness for true inside-out anti-aging effects.

Clinically Proven Plant Stem Cells Go Beyond Surface-Level Skincare

Swiss researchers at Mibelle have developed the PhytoCellTec™ Exosomes technology, using natural Goji Stem Cell Extract to stimulate exosome production. This powerful natural ingredient demonstrates "dual action", promoting keratinocyte differentiation and the expression of epidermal growth and antioxidant-related genes to reinforce the skin's outer barrier.

Meanwhile, it reactivates mesenchymal stem cells (MSCs), boosting collagen synthesis and cellular vitality to enhance skin elasticity and density. Clinical studies show that a cream containing just 0.4% of Goji Stem Cell Extract significantly reduces fine lines and wrinkles after 56 days. Results can be seen in just 28 days with improved skin density and facial contour, and even firmness and lifting effects when applied to the breast area, showcasing its applications well beyond facial skincare.

Exosomes in Daily Skincare and Medical Aesthetics

With proven regenerative and wound-healing properties, exosomes are emerging as a viable alternative to stem cell therapies. As non-living biological elements, they are more stable and easier to handle. Exosome-based serums are particularly effective when used with microneedling, enabling deep skin repair and faster healing.

Plant-derived exosomes have been shown to be bioavailable to mammalian cells and exhibit anti-inflammatory, antioxidant, anti-tumour, and skin-repairing benefits. Recent studies confirm their ability to combat skin aging, reinforcing their growing role in both cosmetic dermatology and everyday skincare. As this technology evolves, it promises a new era of personalized, science-backed beauty.

Dual Stem Cell Formula: "Swiss StemGlow Jelly" Nourishes Youthful Skin from Within; The brand "LAB 91" Unveils Advanced Microneedle Skincare Powered by Deep Cellular Repair

The Swiss StemGlow Jelly is an edible functional jelly formulated with dual stem cell active ingredients, Swiss apple stem cells and grape stem cells. These ingredients are renowned for enhancing cellular vitality, delivering antioxidant protection, and shielding the skin from UV damage.

Meanwhile, LAB 91, a Swiss-made brand, specializes in microneedle skincare solutions. Its signature innovation, the Dual Plant Stem Cell Exosome Complex, combines rare Swiss apple stem cells with goji stem cells to deeply penetrate the skin and trigger cellular repair. Proven results include improved skin elasticity, lifted facial contours, and visibly diminished wrinkles.

The brand offers a range of ampoule serums tailored to various skin concerns, including anti-aging, brightening and intensive repair. Together, the edible jelly and topical microneedle treatments deliver synergistic, cell-level rejuvenation from the inside out.

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About ESDlife

ESDlife, a joint venture of CK Hutchison (formerly Hutchison Whampoa) and Hewlett-Packard HK SAR, operates the award-winning website () and establishes it as one of the most popular and trusted online lifestyle media in Hong Kong. The online platform of ESDlife is furnished with a wide range of lifestyles information under the categories of Wedding, Family and Health. In addition to the prominent No. 1 position of its Wedding Channel in Hong Kong, an e-commerce platform is provided to consumers by offering medical check-up ordering services. ESDlife also delivers integrated marketing and digital solutions to diversified corporate clients.

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